BDBM50032670 4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-ethyl]-benzoic acid::CHEMBL110629

SMILES: Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C

InChI Key: InChIKey=PMIFCTYXFYHHCF-UHFFFAOYSA-N

Data: 3 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50032670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid X receptor gamma (Mus musculus)	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-gamma was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-beta was determined in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-alpha was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-beta was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-gamma was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032670 (4-[1-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES Cc1cc2c(cc1C(C)(C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H32O2/c1-16-14-20-21(24(4,5)13-12-23(20,2)3)15-19(16)25(6,7)18-10-8-17(9-11-18)22(26)27/h8-11,14-15H,12-13H2,1-7H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to bind directly to Retinoic acid receptor RXR-alpha was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair