BDBM50032673 2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-benzoic acid::CHEMBL105806

SMILES: Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C

InChI Key: InChIKey=TVFDRZUBPCJTOL-UHFFFAOYSA-N

Data: 3 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50032673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid X receptor gamma (Mus musculus)	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-gamma was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-beta was determined in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-alpha was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-gamma was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-beta was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032673 (2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...) Show SMILES Cc1cc2c(cc1C(=O)c1ccccc1C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-8-6-7-9-16(15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to bind directly to Retinoic acid receptor RXR-alpha was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair