BDBM50032825 CHEMBL3355183

SMILES: Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NC1CNC1

InChI Key: InChIKey=SADIOHYAMYOCER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50032825 (CHEMBL3355183) Show SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NC1CNC1 Show InChI InChI=1S/C20H19ClN6O2/c21-17-6-1-2-7-18(17)26-20(29)25-15-11-23-27(12-15)16-5-3-4-13(8-16)19(28)24-14-9-22-10-14/h1-8,11-12,14,22H,9-10H2,(H,24,28)(H2,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50032825 (CHEMBL3355183) Show SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NC1CNC1 Show InChI InChI=1S/C20H19ClN6O2/c21-17-6-1-2-7-18(17)26-20(29)25-15-11-23-27(12-15)16-5-3-4-13(8-16)19(28)24-14-9-22-10-14/h1-8,11-12,14,22H,9-10H2,(H,24,28)(H2,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assay				J Med Chem 57: 10013-30 (2014) Article DOI: 10.1021/jm501256y BindingDB Entry DOI: 10.7270/Q25140TS
					More data for this Ligand-Target Pair