BDBM50032922 CHEMBL1701516

SMILES: COc1cccc(c1)C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCCC1

InChI Key: InChIKey=LYNKKLBMQLJMQE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50032922 (CHEMBL1701516) Show SMILES COc1cccc(c1)C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCCC1 Show InChI InChI=1S/C21H24N4O3/c1-23-18-12-16(22-20(26)14-7-6-8-15(11-14)28-3)17(25-9-4-5-10-25)13-19(18)24(2)21(23)27/h6-8,11-13H,4-5,9-10H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to 6H-Flag-tagged Tev-BRPF1 (622-738 aa) (unknown origin) by TR-FRET competitive assay				ACS Med Chem Lett 5: 1190-5 (2014) Article DOI: 10.1021/ml5002932 BindingDB Entry DOI: 10.7270/Q2445P29
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50032922 (CHEMBL1701516) Show SMILES COc1cccc(c1)C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCCC1 Show InChI InChI=1S/C21H24N4O3/c1-23-18-12-16(22-20(26)14-7-6-8-15(11-14)28-3)17(25-9-4-5-10-25)13-19(18)24(2)21(23)27/h6-8,11-13H,4-5,9-10H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to 6His-tagged-BRD4 BD1 Y390A mutant (1 to 477 aa) (unknown origin) by TR-FRET competitive assay				ACS Med Chem Lett 5: 1190-5 (2014) Article DOI: 10.1021/ml5002932 BindingDB Entry DOI: 10.7270/Q2445P29
					More data for this Ligand-Target Pair