BDBM50033139 CHEMBL2370495::H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*-Arg*-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH

SMILES: [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O

InChI Key: InChIKey=VNNOAPBNQWNWSP-PGGYXFKHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50033139 (CHEMBL2370495 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*...) Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O Show InChI InChI=1S/C63H106N20O11/c1-5-39(4)53(61(94)76-42(18-9-11-27-64)37-83-31-15-22-50(83)60(93)78-45(54(67)87)19-10-12-28-65)82-57(90)47(21-14-30-73-63(70)71)79-56(89)46(20-13-29-72-62(68)69)80-58(91)48(32-38(2)3)81-59(92)49(34-40-16-7-6-8-17-40)77-52(86)36-74-51(85)35-75-55(88)44(66)33-41-23-25-43(84)26-24-41/h6-8,16-17,23-26,38-39,42,44-50,53,84H,5,9-15,18-22,27-37,64-66H2,1-4H3,(H2,67,87)(H,74,85)(H,75,88)(H,76,94)(H,77,86)(H,78,93)(H,79,89)(H,80,91)(H,81,92)(H,82,90)(H4,68,69,72)(H4,70,71,73)/t39-,42-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 from Guinea pig brain homogenate using [3H]-DAMGO				J Med Chem 38: 3462-8 (1995) BindingDB Entry DOI: 10.7270/Q2QZ291Q
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50033139 (CHEMBL2370495 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*...) Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O Show InChI InChI=1S/C63H106N20O11/c1-5-39(4)53(61(94)76-42(18-9-11-27-64)37-83-31-15-22-50(83)60(93)78-45(54(67)87)19-10-12-28-65)82-57(90)47(21-14-30-73-63(70)71)79-56(89)46(20-13-29-72-62(68)69)80-58(91)48(32-38(2)3)81-59(92)49(34-40-16-7-6-8-17-40)77-52(86)36-74-51(85)35-75-55(88)44(66)33-41-23-25-43(84)26-24-41/h6-8,16-17,23-26,38-39,42,44-50,53,84H,5,9-15,18-22,27-37,64-66H2,1-4H3,(H2,67,87)(H,74,85)(H,75,88)(H,76,94)(H,77,86)(H,78,93)(H,79,89)(H,80,91)(H,81,92)(H,82,90)(H4,68,69,72)(H4,70,71,73)/t39-,42-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of Guinea pig brain homogenate using [3H]U-69,593				J Med Chem 38: 3462-8 (1995) BindingDB Entry DOI: 10.7270/Q2QZ291Q
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50033139 (CHEMBL2370495 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*...) Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O Show InChI InChI=1S/C63H106N20O11/c1-5-39(4)53(61(94)76-42(18-9-11-27-64)37-83-31-15-22-50(83)60(93)78-45(54(67)87)19-10-12-28-65)82-57(90)47(21-14-30-73-63(70)71)79-56(89)46(20-13-29-72-62(68)69)80-58(91)48(32-38(2)3)81-59(92)49(34-40-16-7-6-8-17-40)77-52(86)36-74-51(85)35-75-55(88)44(66)33-41-23-25-43(84)26-24-41/h6-8,16-17,23-26,38-39,42,44-50,53,84H,5,9-15,18-22,27-37,64-66H2,1-4H3,(H2,67,87)(H,74,85)(H,75,88)(H,76,94)(H,77,86)(H,78,93)(H,79,89)(H,80,91)(H,81,92)(H,82,90)(H4,68,69,72)(H4,70,71,73)/t39-,42-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor of Guinea pig brain homogenate using [3H]c[D-Pen2,p-Cl-Phe4,D-Pen5]enkephalin				J Med Chem 38: 3462-8 (1995) BindingDB Entry DOI: 10.7270/Q2QZ291Q
					More data for this Ligand-Target Pair