BDBM50033578 9b-Phenyl-2,3-dihydro-9bH-thiazolo[2,3-a]isoindol-5-one::CHEMBL163536

SMILES: O=C1c2ccccc2[C@@]23CC=CCC12c1ccccc1C3=O

InChI Key: InChIKey=NLDWZYHDLKKMTL-FIWHBWSRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033578 (9b-Phenyl-2,3-dihydro-9bH-thiazolo[2,3-a]isoindol-...) Show SMILES O=C1c2ccccc2[C@@]23CC=CCC12c1ccccc1C3=O |c:11| Show InChI InChI=1S/C20H14O2/c21-17-13-7-1-3-9-15(13)19-11-5-6-12-20(17,19)16-10-4-2-8-14(16)18(19)22/h1-10H,11-12H2/t19-,20?/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Mannheim GmbH Curated by ChEMBL					Assay Description In vitro for inhibitory activity against HIV-1 Reverse Transcriptase				J Med Chem 36: 726-32 (1993) BindingDB Entry DOI: 10.7270/Q2ZG6R9J
					More data for this Ligand-Target Pair