BDBM50033628 CHEMBL3358142
SMILES: [O-]C(=O)C(F)(F)F.COC1=CC(=O)N([C@H]1Cc1ccc(O)cc1)C(=O)\C=C\[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)[NH+](C)C
InChI Key: InChIKey=XSADKPNQNYOYQO-JVTILXPNSA-O
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Falcipain 2 (Plasmodium falciparum) | BDBM50033628 (CHEMBL3358142) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ... | J Med Chem 57: 10557-63 (2014) Article DOI: 10.1021/jm501439w BindingDB Entry DOI: 10.7270/Q2TM7CQW | |||||||||||
More data for this Ligand-Target Pair |