BDBM50033659 CHEMBL3358140

SMILES: [O-]C(=O)C(F)(F)F.COC1=CC(=O)N(C1)C(=O)\C=C\[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)[NH+](C)C

InChI Key: InChIKey=BFFLBCSIHCMNEM-LMZUPGNCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Falcipain-2 (Plasmodium falciparum)	BDBM50033659 (CHEMBL3358140) Show SMILES [O-]C(=O)C(F)(F)F.COC1=CC(=O)N(C1)C(=O)\C=C\[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)[NH+](C)C |r,t:8| Show InChI InChI=1S/C29H49N5O6.C2HF3O2/c1-17(2)13-22(27(37)30-20(7)11-12-24(35)34-16-21(40-10)15-25(34)36)31-28(38)23(14-18(3)4)32-29(39)26(19(5)6)33(8)9;3-2(4,5)1(6)7/h11-12,15,17-20,22-23,26H,13-14,16H2,1-10H3,(H,30,37)(H,31,38)(H,32,39);(H,6,7)/b12-11+;/t20-,22-,23-,26-;/m0./s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...				J Med Chem 57: 10557-63 (2014) Article DOI: 10.1021/jm501439w BindingDB Entry DOI: 10.7270/Q2TM7CQW
					More data for this Ligand-Target Pair