BDBM50033961 1-{5-[4,5-Bis-(2-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-3-(2,4-difluoro-phenyl)-1-heptyl-urea::CHEMBL11072

SMILES: CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1OC)-c1ccccc1OC)C(=O)Nc1ccc(F)cc1F

InChI Key: InChIKey=IYQBINNYAYABDD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50033961 (1-{5-[4,5-Bis-(2-methoxy-phenyl)-1H-imidazol-2-yls...) Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1OC)-c1ccccc1OC)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C36H44F2N4O3S/c1-4-5-6-7-13-22-42(36(43)39-30-21-20-26(37)25-29(30)38)23-14-8-15-24-46-35-40-33(27-16-9-11-18-31(27)44-2)34(41-35)28-17-10-12-19-32(28)45-3/h9-12,16-21,25H,4-8,13-15,22-24H2,1-3H3,(H,39,43)(H,40,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.				J Med Chem 38: 1067-83 (1995) BindingDB Entry DOI: 10.7270/Q28S4P0T
					More data for this Ligand-Target Pair