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BDBM50033985 CHEMBL11071::{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-heptyl-carbamic acid phenyl ester

SMILES: CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)C(=O)Oc1ccccc1

InChI Key: InChIKey=IKWUUFRYJJHPBS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033985   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)		BDBM50033985
PNG
(CHEMBL11071 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)C(=O)Oc1ccccc1
Show InChI InChI=1S/C36H45N3O4S/c1-4-5-6-7-12-25-39(36(40)43-32-15-10-8-11-16-32)26-13-9-14-27-44-35-37-33(28-17-21-30(41-2)22-18-28)34(38-35)29-19-23-31(42-3)24-20-29/h8,10-11,15-24H,4-7,9,12-14,25-27H2,1-3H3,(H,37,38)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 640n/an/an/an/an/an/a



DuPont Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.

J Med Chem 38: 1067-83 (1995)


BindingDB Entry DOI: 10.7270/Q28S4P0T
More data for this
Ligand-Target Pair