null

SMILES: O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1

InChI Key: InChIKey=XDGMPBUKARQUCK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50033999 (3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...) Show SMILES O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C21H25NO/c23-21(20-9-5-2-6-10-20)12-11-18-13-15-22(16-14-18)17-19-7-3-1-4-8-19/h1-10,18H,11-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro (UFRJ) Curated by ChEMBL					Assay Description Inhibition of human acetylcholinesterase				Eur J Med Chem 46: 39-51 (2010) Article DOI: 10.1016/j.ejmech.2010.10.009 BindingDB Entry DOI: 10.7270/Q2SX6FG0
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50033999 (3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...) Show SMILES O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C21H25NO/c23-21(20-9-5-2-6-10-20)12-11-18-13-15-22(16-14-18)17-19-7-3-1-4-8-19/h1-10,18H,11-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitro				J Med Chem 38: 1084-9 (1995) BindingDB Entry DOI: 10.7270/Q21N81S7
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50033999 (3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...) Show SMILES O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C21H25NO/c23-21(20-9-5-2-6-10-20)12-11-18-13-15-22(16-14-18)17-19-7-3-1-4-8-19/h1-10,18H,11-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitro				J Med Chem 38: 1084-9 (1995) BindingDB Entry DOI: 10.7270/Q21N81S7
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50033999 (3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...) Show SMILES O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C21H25NO/c23-21(20-9-5-2-6-10-20)12-11-18-13-15-22(16-14-18)17-19-7-3-1-4-8-19/h1-10,18H,11-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of AChE				Eur J Med Chem 45: 1167-72 (2010) Article DOI: 10.1016/j.ejmech.2009.12.038 BindingDB Entry DOI: 10.7270/Q25H7GFM
					More data for this Ligand-Target Pair