Found 12 hits for monomerid = 50034110 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligand |
J Med Chem 40: 2003-10 (1997)
Article DOI: 10.1021/jm960653j BindingDB Entry DOI: 10.7270/Q2CR5X2K |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligand |
J Med Chem 40: 1990-2002 (1997)
Article DOI: 10.1021/jm960651z BindingDB Entry DOI: 10.7270/Q2HD7ZCK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit&aagrove; degli Studi di Milano
Curated by PDSP Ki Database
| |
Br J Pharmacol 124: 485-92 (1998)
Article DOI: 10.1038/sj.bjp.0701860 BindingDB Entry DOI: 10.7270/Q29885KW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit&agrove; degli Studi di Milano
Curated by PDSP Ki Database
| |
Br J Pharmacol 127: 1288-94 (1999)
Article DOI: 10.1038/sj.bjp.0702658 BindingDB Entry DOI: 10.7270/Q20G3HQ6 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.0570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Urbino
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]iodomelatonin binding to melatonin receptor in quail brain as 1/Ka |
J Med Chem 36: 4069-74 (1993)
Article DOI: 10.1021/jm00077a010 BindingDB Entry DOI: 10.7270/Q2KP84VP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor type 1C
(Gallus gallus) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.0596 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity in chicken brain membranes by using [2-125I]melatonin in a competition radioligand binding assay |
J Med Chem 38: 1132-9 (1995)
Article DOI: 10.1021/jm00007a010 BindingDB Entry DOI: 10.7270/Q2HM5C6M |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King's College
Curated by PDSP Ki Database
| |
Biol Cell 89: 531-7 (1997)
Article DOI: 10.1016/s0248-4900(98)80009-9 BindingDB Entry DOI: 10.7270/Q2JS9P06 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King's College
Curated by PDSP Ki Database
| |
Biol Cell 89: 531-7 (1997)
Article DOI: 10.1016/s0248-4900(98)80009-9 BindingDB Entry DOI: 10.7270/Q2JS9P06 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Massachusetts General Hospital
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 92: 8734-8 (1995)
Article DOI: 10.1073/pnas.92.19.8734 BindingDB Entry DOI: 10.7270/Q2GH9GGM |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Massachusetts General Hospital
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 92: 8734-8 (1995)
Article DOI: 10.1073/pnas.92.19.8734 BindingDB Entry DOI: 10.7270/Q2GH9GGM |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 0.0620 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as radiolabeled ligand |
J Med Chem 40: 1990-2002 (1997)
Article DOI: 10.1021/jm960651z BindingDB Entry DOI: 10.7270/Q2HD7ZCK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50034110
(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)Show InChI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 0.0620 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligand |
J Med Chem 40: 2003-10 (1997)
Article DOI: 10.1021/jm960653j BindingDB Entry DOI: 10.7270/Q2CR5X2K |
More data for this Ligand-Target Pair | 3D Structure (crystal) |