BDBM50034458 5-Isopropylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL416026

SMILES: CC(C)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=IOVMJAOVAQFLLK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50034458 (5-Isopropylamino-naphthalene-1-sulfonic acid (3,4-...) Show SMILES CC(C)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C18H21N3O3S/c1-11(2)19-16-9-5-8-15-14(16)7-6-10-17(15)25(22,23)21-18-12(3)13(4)20-24-18/h5-11,19,21H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells				J Med Chem 38: 659-68 (1995) BindingDB Entry DOI: 10.7270/Q2D799G5
					More data for this Ligand-Target Pair
EDNRA (RAT)	BDBM50034458 (5-Isopropylamino-naphthalene-1-sulfonic acid (3,4-...) Show SMILES CC(C)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C18H21N3O3S/c1-11(2)19-16-9-5-8-15-14(16)7-6-10-17(15)25(22,23)21-18-12(3)13(4)20-24-18/h5-11,19,21H,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.				J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS
					More data for this Ligand-Target Pair