null

SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1noc(C)c1C

InChI Key: InChIKey=NSGBGAYOKDUSNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (RAT)	BDBM50034488 (5-Dimethylamino-naphthalene-1-sulfonic acid (4,5-d...) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1noc(C)c1C Show InChI InChI=1S/C17H19N3O3S/c1-11-12(2)23-18-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10H,1-4H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cells				J Med Chem 38: 659-68 (1995) BindingDB Entry DOI: 10.7270/Q2D799G5
					More data for this Ligand-Target Pair
Endothelin-1 receptor (RAT)	BDBM50034488 (5-Dimethylamino-naphthalene-1-sulfonic acid (4,5-d...) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1noc(C)c1C Show InChI InChI=1S/C17H19N3O3S/c1-11-12(2)23-18-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10H,1-4H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.				J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS
					More data for this Ligand-Target Pair