BDBM50034497 CHEMBL3359263
SMILES: CCn1ncc2CC3(CCN(CC3)C(=O)c3ccc4[nH]ncc4c3)CC(=O)c12
InChI Key: InChIKey=NTZNNYUOWHCXTM-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human)) | BDBM50034497 (CHEMBL3359263) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 317 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant ACC1 after 1 hr by transcreener assay | J Med Chem 57: 10512-26 (2014) Article DOI: 10.1021/jm5016022 BindingDB Entry DOI: 10.7270/Q2SN0BJM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human)) | BDBM50034497 (CHEMBL3359263) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant ACC2 after 1 hr by transcreener assay | J Med Chem 57: 10512-26 (2014) Article DOI: 10.1021/jm5016022 BindingDB Entry DOI: 10.7270/Q2SN0BJM | |||||||||||
More data for this Ligand-Target Pair |