null

SMILES: CC(C)Oc1ccc(cc1Cl)-c1nc(no1)-c1cccc2CCN(CC(O)=O)CCc12

InChI Key: InChIKey=LPIQDXLGZWUWJI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50034572 (CHEMBL3359838) Show SMILES CC(C)Oc1ccc(cc1Cl)-c1nc(no1)-c1cccc2CCN(CC(O)=O)CCc12 Show InChI InChI=1S/C23H24ClN3O4/c1-14(2)30-20-7-6-16(12-19(20)24)23-25-22(26-31-23)18-5-3-4-15-8-10-27(13-21(28)29)11-9-17(15)18/h3-7,12,14H,8-11,13H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human S1P1R expressed in RH7777 membranes assessed as [35S]GTPgammaS binding after 30 mins				J Med Chem 57: 10424-42 (2014) Article DOI: 10.1021/jm5010336 BindingDB Entry DOI: 10.7270/Q2DF6SSX
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50034572 (CHEMBL3359838) Show SMILES CC(C)Oc1ccc(cc1Cl)-c1nc(no1)-c1cccc2CCN(CC(O)=O)CCc12 Show InChI InChI=1S/C23H24ClN3O4/c1-14(2)30-20-7-6-16(12-19(20)24)23-25-22(26-31-23)18-5-3-4-15-8-10-27(13-21(28)29)11-9-17(15)18/h3-7,12,14H,8-11,13H2,1-2H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<3.16E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human S1P3R expressed in RBL membranes assessed as [35S]GTPgammaS binding after 30 mins				J Med Chem 57: 10424-42 (2014) Article DOI: 10.1021/jm5010336 BindingDB Entry DOI: 10.7270/Q2DF6SSX
					More data for this Ligand-Target Pair