BDBM50034669 CHEMBL290189::Phosphoric acid dimethyl ester 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester

SMILES: COP(=O)(OC)OCN1C(=O)c2ccccc2S1(=O)=O

InChI Key: InChIKey=TTWVPXBPTQRGHW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50034669 (CHEMBL290189 | Phosphoric acid dimethyl ester 1,1,...) Show SMILES COP(=O)(OC)OCN1C(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C10H12NO7PS/c1-16-19(13,17-2)18-7-11-10(12)8-5-3-4-6-9(8)20(11,14)15/h3-6H,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibitory activity against Human leukocyte elastase was determined				J Med Chem 38: 1571-4 (1995) BindingDB Entry DOI: 10.7270/Q2M32TS7
					More data for this Ligand-Target Pair