BDBM50035057 (eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::CHEMBL282614::Eltoprazine

SMILES: C1CN(CCN1)c1cccc2OCCOc12

InChI Key: InChIKey=WVLHGCRWEHCIOT-UHFFFAOYSA-N

Data: 42 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50035057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 337-52 (1994) Article DOI: 10.1016/j.bioorg.2015.06.004 BindingDB Entry DOI: 10.7270/Q2H130HG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement				J Med Chem 39: 126-34 (1996) Article DOI: 10.1021/jm950410b BindingDB Entry DOI: 10.7270/Q2VX0K7V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homo...				J Med Chem 38: 1942-54 (1995) BindingDB Entry DOI: 10.7270/Q2SN080M
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	53.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1B receptor				J Med Chem 38: 4044-55 (1995) BindingDB Entry DOI: 10.7270/Q2KP83C0
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	53.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 337-52 (1994) Article DOI: 10.1016/j.bioorg.2015.06.004 BindingDB Entry DOI: 10.7270/Q2H130HG
					More data for this Ligand-Target Pair
HTR2C (PIG)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
HTR2C (PIG)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 337-52 (1994) Article DOI: 10.1016/j.bioorg.2015.06.004 BindingDB Entry DOI: 10.7270/Q2H130HG
					More data for this Ligand-Target Pair
HTR1D (Bos taurus (Bovine))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 337-52 (1994) Article DOI: 10.1016/j.bioorg.2015.06.004 BindingDB Entry DOI: 10.7270/Q2H130HG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP Ki Database									J Pharmacol Exp Ther 268: 337-52 (1994) Article DOI: 10.1016/j.bioorg.2015.06.004 BindingDB Entry DOI: 10.7270/Q2H130HG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Substance K (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
TRH (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Glycine (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Calcium channel (DHP) (Homo sapiens (Human))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel (Homo sapiens (Human))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar B.V. Curated by PDSP Ki Database									Drug Metabol Drug Interact 8: 85-114 (1990) Article DOI: 10.1515/dmdi.1990.8.1-2.85 BindingDB Entry DOI: 10.7270/Q27M06DV
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50035057 ((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...) Show SMILES C1CN(CCN1)c1cccc2OCCOc12 Show InChI InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Ltd. Curated by ChEMBL					Assay Description Binding affinity to His-tagged human beta1 adrenergic receptor expressed in HEK293 cell membranes by surface plasmon resonance analysis				J Med Chem 56: 3446-55 (2013) Article DOI: 10.1021/jm400140q BindingDB Entry DOI: 10.7270/Q26M386T
					More data for this Ligand-Target Pair