BDBM50035202 CHEMBL291857::N-[2-(2,7-Dimethoxy-naphthalen-1-yl)-ethyl]-propionamide

SMILES: CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12

InChI Key: InChIKey=SUFMDDIORSWOHT-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50035202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melatonin receptor type 1C (Gallus gallus)	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes				J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H
					More data for this Ligand-Target Pair
Melatonin receptor type 1C (Gallus gallus)	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-Sud Curated by ChEMBL					Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand				J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1A expressed in CHO cells				J Med Chem 40: 4195-8 (1998) Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells				Bioorg Med Chem Lett 7: 2409-2414 (1997) Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of the 2-[125I]- iodomelatonin binding to Melatonin receptor type 1B expressed in CHO cells				J Med Chem 40: 4195-8 (1998) Article DOI: 10.1021/jm970437q BindingDB Entry DOI: 10.7270/Q2930S90
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) Show SMILES CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 Show InChI InChI=1S/C17H21NO3/c1-4-17(19)18-10-9-14-15-11-13(20-2)7-5-12(15)6-8-16(14)21-3/h5-8,11H,4,9-10H2,1-3H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells				Bioorg Med Chem Lett 7: 2409-2414 (1997) Article DOI: 10.1016/S0960-894X(97)00444-7 BindingDB Entry DOI: 10.7270/Q25T3KFF
					More data for this Ligand-Target Pair