BDBM50035316 (8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-phenyl-methanone::CHEMBL302994

SMILES: CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)c4ccccc4)c3c2C1

InChI Key: InChIKey=WYHYLXRVYVASMT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035316 ((8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]ind...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)c4ccccc4)c3c2C1 Show InChI InChI=1S/C25H30N2O/c1-3-14-27(15-4-2)20-12-10-18-11-13-23-24(21(18)16-20)22(17-26-23)25(28)19-8-6-5-7-9-19/h5-9,11,13,17,20,26H,3-4,10,12,14-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50035316 ((8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]ind...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)c4ccccc4)c3c2C1 Show InChI InChI=1S/C25H30N2O/c1-3-14-27(15-4-2)20-12-10-18-11-13-23-24(21(18)16-20)22(17-26-23)25(28)19-8-6-5-7-9-19/h5-9,11,13,17,20,26H,3-4,10,12,14-16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D3 expressed in CHO-K1 cells, using [3H]-spiperone as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035316 ((8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]ind...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)c4ccccc4)c3c2C1 Show InChI InChI=1S/C25H30N2O/c1-3-14-27(15-4-2)20-12-10-18-11-13-23-24(21(18)16-20)22(17-26-23)25(28)19-8-6-5-7-9-19/h5-9,11,13,17,20,26H,3-4,10,12,14-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]-U-86,170 as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair