BDBM50035325 (4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL71663

SMILES: CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1

InChI Key: InChIKey=HCDLXJXEGJTMHB-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035325 ((4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 Show InChI InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 from CHO-K1 cells, using [3H]-U-86,170 as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035325 ((4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 Show InChI InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035325 ((4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 Show InChI InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]-8-OH-DPAT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50035325 ((4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 Show InChI InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D3 from CHO-K1 cells, using [3H]-spiperone as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50035325 ((4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 Show InChI InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Göteborg University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor beta expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.				J Med Chem 38: 2202-16 (1995) BindingDB Entry DOI: 10.7270/Q24T6HD0
					More data for this Ligand-Target Pair