BDBM50035339 CHEMBL3343364

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=QOBYLORHSHBOAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035339 (CHEMBL3343364) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H33FN6O4/c1-22-32(37-38-40(22)24-9-4-3-5-10-24)33(41)36-23-11-12-29(26(34)19-23)44-28-13-14-35-27-21-31(30(42-2)20-25(27)28)43-18-8-17-39-15-6-7-16-39/h3-5,9-14,19-21H,6-8,15-18H2,1-2H3,(H,36,41)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
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