BDBM50035404 CHEMBL3343380

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=LSMQAIIXZQNXQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035404 (CHEMBL3343380) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C34H35FN6O4/c1-23-33(38-39-41(23)25-10-5-3-6-11-25)34(42)37-24-12-13-30(27(35)20-24)45-29-14-15-36-28-22-32(31(43-2)21-26(28)29)44-19-9-18-40-16-7-4-8-17-40/h3,5-6,10-15,20-22H,4,7-9,16-19H2,1-2H3,(H,37,42)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
					More data for this Ligand-Target Pair