BDBM50035408 CHEMBL3343382

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=OIIPGLWIAWFBQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50035408 (CHEMBL3343382) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C34H31F5N6O4/c1-47-29-19-24-26(20-30(29)48-17-5-16-44-14-3-2-4-15-44)40-13-12-27(24)49-28-11-8-22(18-25(28)36)41-33(46)31-32(34(37,38)39)45(43-42-31)23-9-6-21(35)7-10-23/h6-13,18-20H,2-5,14-17H2,1H3,(H,41,46)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 22: 6438-52 (2014) Article DOI: 10.1016/j.bmc.2014.09.037 BindingDB Entry DOI: 10.7270/Q2BG2QM2
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