BDBM50035963 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (4-amino-butyl)-amide; hydrochloride::CHEMBL543903

SMILES: NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F

InChI Key: InChIKey=MKWDKVONNBXTHL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair