null

SMILES: CCCSc1nsnc1C1=CCN(C)CC1

InChI Key: InChIKey=MRQUPRPEAWUIHE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50035989 (1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCN(C)CC1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-8-15-11-10(12-16-13-11)9-4-6-14(2)7-5-9/h4H,3,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description In vitro binding affinity towards Muscarinic acetylcholine receptor M2 was determined by measuring its ability to displace [3H]-AF-DX 384 from rat he...				J Med Chem 38: 5-8 (1995) BindingDB Entry DOI: 10.7270/Q2BC3XMW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035989 (1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCN(C)CC1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-8-15-11-10(12-16-13-11)9-4-6-14(2)7-5-9/h4H,3,5-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description In vitro binding affinity towards Sigma receptor type 1 was determined by measuring its ability to displace [3H]-(+)-pentazocine from guinea pig brai...				J Med Chem 38: 5-8 (1995) BindingDB Entry DOI: 10.7270/Q2BC3XMW
					More data for this Ligand-Target Pair
Muscarinic receptor M1 (Bos taurus)	BDBM50035989 (1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCN(C)CC1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-8-15-11-10(12-16-13-11)9-4-6-14(2)7-5-9/h4H,3,5-8H2,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description In vitro binding affinity towards Muscarinic acetylcholine receptor M1 was determined by measuring its ability to displace [3H]-Pirenzepine from bovi...				J Med Chem 38: 5-8 (1995) BindingDB Entry DOI: 10.7270/Q2BC3XMW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50035989 (1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCN(C)CC1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-8-15-11-10(12-16-13-11)9-4-6-14(2)7-5-9/h4H,3,5-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description In vitro binding affinity towards Muscarinic acetylcholine receptor M3 was determined by measuring its ability to displace [3H]-N-methyl- scopolamine...				J Med Chem 38: 5-8 (1995) BindingDB Entry DOI: 10.7270/Q2BC3XMW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50035989 (1-Methyl-4-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCN(C)CC1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-8-15-11-10(12-16-13-11)9-4-6-14(2)7-5-9/h4H,3,5-8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description In vitro binding affinity towards Sigma receptor type 2 was determined by measuring its ability to displace [3H]-1,3-di-o-tolylguanidine from rat liv...				J Med Chem 38: 5-8 (1995) BindingDB Entry DOI: 10.7270/Q2BC3XMW
					More data for this Ligand-Target Pair