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BDBM50036394 CHEMBL163611::N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-methyl]-4-methoxy-phenoxy}-3,5-dimethyl-phenyl)-oxalamic acid ethyl ester

SMILES: CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc(OC)c(c2)C(O)c2ccc(F)cc2)c(C)c1

InChI Key: InChIKey=XJRSOPNLGPSYCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
thyroid beta


(RAT)
BDBM50036394
PNG
(CHEMBL163611 | N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc(OC)c(c2)C(O)c2ccc(F)cc2)c(C)c1
Show InChI InChI=1S/C26H26FNO6/c1-5-33-26(31)25(30)28-19-12-15(2)24(16(3)13-19)34-20-10-11-22(32-4)21(14-20)23(29)17-6-8-18(27)9-7-17/h6-14,23,29H,5H2,1-4H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 34n/an/an/an/an/an/a



Ciba Pharmaceuticals

Curated by ChEMBL


Assay Description
Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.


J Med Chem 38: 695-707 (1995)


BindingDB Entry DOI: 10.7270/Q2T43TRC
More data for this
Ligand-Target Pair