BDBM50036405 CHEMBL434476::N-(3,5-Dichloro-4-{3-[(4-chloro-phenyl)-hydroxy-methyl]-4-hydroxy-phenoxy}-phenyl)-oxalamic acid

SMILES: OC(c1ccc(Cl)cc1)c1cc(Oc2c(Cl)cc(NC(=O)C(O)=O)cc2Cl)ccc1O

InChI Key: InChIKey=YKTQRPRPHNKHPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036405 (CHEMBL434476 | N-(3,5-Dichloro-4-{3-[(4-chloro-phe...) Show SMILES OC(c1ccc(Cl)cc1)c1cc(Oc2c(Cl)cc(NC(=O)C(O)=O)cc2Cl)ccc1O Show InChI InChI=1S/C21H14Cl3NO6/c22-11-3-1-10(2-4-11)18(27)14-9-13(5-6-17(14)26)31-19-15(23)7-12(8-16(19)24)25-20(28)21(29)30/h1-9,18,26-27H,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair