BDBM50036406 CHEMBL163380::[3,5-Dichloro-4-(4-hydroxy-3-isopropyl-phenoxy)-phenylamino]-acetic acid

SMILES: CC(C)c1cc(Oc2c(Cl)cc(NCC(O)=O)cc2Cl)ccc1O

InChI Key: InChIKey=CTNFCDIJTMBRPS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036406 (CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc(NCC(O)=O)cc2Cl)ccc1O Show InChI InChI=1S/C17H17Cl2NO4/c1-9(2)12-7-11(3-4-15(12)21)24-17-13(18)5-10(6-14(17)19)20-8-16(22)23/h3-7,9,20-21H,8H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair
thyroid beta (RAT)	BDBM50036406 (CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc(NCC(O)=O)cc2Cl)ccc1O Show InChI InChI=1S/C17H17Cl2NO4/c1-9(2)12-7-11(3-4-15(12)21)24-17-13(18)5-10(6-14(17)19)20-8-16(22)23/h3-7,9,20-21H,8H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of bound [125I]L-T3 rat plasma membrane 3,5,3'' L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair