BDBM50036415 CHEMBL163268::N-[3,5-Dibromo-4-(4-hydroxy-3-isopropyl-phenoxy)-phenyl]-oxalamide

SMILES: CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(N)=O)cc2Br)ccc1O

InChI Key: InChIKey=BWKFMYFCGATJOE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036415 (CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...) Show SMILES CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(N)=O)cc2Br)ccc1O Show InChI InChI=1S/C17H16Br2N2O4/c1-8(2)11-7-10(3-4-14(11)22)25-15-12(18)5-9(6-13(15)19)21-17(24)16(20)23/h3-8,22H,1-2H3,(H2,20,23)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair
thyroid beta (RAT)	BDBM50036415 (CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...) Show SMILES CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(N)=O)cc2Br)ccc1O Show InChI InChI=1S/C17H16Br2N2O4/c1-8(2)11-7-10(3-4-14(11)22)25-15-12(18)5-9(6-13(15)19)21-17(24)16(20)23/h3-8,22H,1-2H3,(H2,20,23)(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of bound [125I]L-T3 rat plasma membrane 3,5,3'' L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair