BDBM50036416 2-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenylamino]-3-phenyl-propionic acid::CHEMBL350930

SMILES: CC(C)c1cc(Oc2c(C)cc(NC(Cc3ccccc3)C(O)=O)cc2C)ccc1O

InChI Key: InChIKey=BECVQSYLFSXWHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036416 (2-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-...) Show SMILES CC(C)c1cc(Oc2c(C)cc(NC(Cc3ccccc3)C(O)=O)cc2C)ccc1O Show InChI InChI=1S/C26H29NO4/c1-16(2)22-15-21(10-11-24(22)28)31-25-17(3)12-20(13-18(25)4)27-23(26(29)30)14-19-8-6-5-7-9-19/h5-13,15-16,23,27-28H,14H2,1-4H3,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair