BDBM50036417 CHEMBL423977::N-{3,5-Dichloro-4-[3-(4-fluoro-benzyl)-4-hydroxy-phenoxy]-phenyl}-oxalamic acid

SMILES: OC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc(O)c(Cc3ccc(F)cc3)c2)c(Cl)c1

InChI Key: InChIKey=RBTLTWAJLHVMTF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036417 (CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...) Show SMILES OC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc(O)c(Cc3ccc(F)cc3)c2)c(Cl)c1 Show InChI InChI=1S/C21H14Cl2FNO5/c22-16-9-14(25-20(27)21(28)29)10-17(23)19(16)30-15-5-6-18(26)12(8-15)7-11-1-3-13(24)4-2-11/h1-6,8-10,26H,7H2,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair
thyroid beta (RAT)	BDBM50036417 (CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...) Show SMILES OC(=O)C(=O)Nc1cc(Cl)c(Oc2ccc(O)c(Cc3ccc(F)cc3)c2)c(Cl)c1 Show InChI InChI=1S/C21H14Cl2FNO5/c22-16-9-14(25-20(27)21(28)29)10-17(23)19(16)30-15-5-6-18(26)12(8-15)7-11-1-3-13(24)4-2-11/h1-6,8-10,26H,7H2,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair