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BDBM50036418 CHEMBL350049::N-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-oxalamic acid ethyl ester

SMILES: CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc(O)c(c2)C(C)C)c(C)c1

InChI Key: InChIKey=BUESDXQGQSWBJR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036418   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
thyroid beta


(RAT)		BDBM50036418
PNG
(CHEMBL350049 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Show SMILES CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc(O)c(c2)C(C)C)c(C)c1
Show InChI InChI=1S/C21H25NO5/c1-6-26-21(25)20(24)22-15-9-13(4)19(14(5)10-15)27-16-7-8-18(23)17(11-16)12(2)3/h7-12,23H,6H2,1-5H3,(H,22,24)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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PubMed
n/an/a 0.230n/an/an/an/an/an/a



Ciba Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor

J Med Chem 38: 695-707 (1995)


BindingDB Entry DOI: 10.7270/Q2T43TRC
More data for this
Ligand-Target Pair