BDBM50036425 2-[3,5-Dichloro-4-(4-hydroxy-3-isopropyl-phenoxy)-phenylamino]-3-phenyl-propionic acid::CHEMBL160203

SMILES: CC(C)c1cc(Oc2c(Cl)cc(NC(Cc3ccccc3)C(O)=O)cc2Cl)ccc1O

InChI Key: InChIKey=NGBYTDSMUBIEGS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036425 (2-[3,5-Dichloro-4-(4-hydroxy-3-isopropyl-phenoxy)-...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc(NC(Cc3ccccc3)C(O)=O)cc2Cl)ccc1O Show InChI InChI=1S/C24H23Cl2NO4/c1-14(2)18-13-17(8-9-22(18)28)31-23-19(25)11-16(12-20(23)26)27-21(24(29)30)10-15-6-4-3-5-7-15/h3-9,11-14,21,27-28H,10H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair