BDBM50036431 2-[3,5-Dichloro-4-(4-hydroxy-3-isopropyl-phenoxy)-phenylamino]-propionic acid::CHEMBL349076

SMILES: CC(C)c1cc(Oc2c(Cl)cc(NC(C)C(O)=O)cc2Cl)ccc1O

InChI Key: InChIKey=LNFCAMOHEJAHKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
thyroid beta (RAT)	BDBM50036431 (2-[3,5-Dichloro-4-(4-hydroxy-3-isopropyl-phenoxy)-...) Show SMILES CC(C)c1cc(Oc2c(Cl)cc(NC(C)C(O)=O)cc2Cl)ccc1O Show InChI InChI=1S/C18H19Cl2NO4/c1-9(2)13-8-12(4-5-16(13)22)25-17-14(19)6-11(7-15(17)20)21-10(3)18(23)24/h4-10,21-22H,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Ciba Pharmaceuticals Curated by ChEMBL					Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.				J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC
					More data for this Ligand-Target Pair