BDBM50036545 CHEMBL3353602
SMILES: CC1(CC1)c1ccc(CN(c2ncc(cc2Cl)C(F)(F)F)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1
InChI Key: InChIKey=CJXHGYWAUTVWDA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human)) | BDBM50036545 (CHEMBL3353602) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
RaQualia Pharma Inc. Curated by ChEMBL | Assay Description Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx | Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX | |||||||||||
More data for this Ligand-Target Pair |