BDBM50036674 CHEMBL3354820

SMILES: Nc1cc(cc(NC2CCCC2)n1)N1CCNCC1

InChI Key: InChIKey=TUVIRBKPSUGSNV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50036674 (CHEMBL3354820) Show SMILES Nc1cc(cc(NC2CCCC2)n1)N1CCNCC1 Show InChI InChI=1S/C14H23N5/c15-13-9-12(19-7-5-16-6-8-19)10-14(18-13)17-11-3-1-2-4-11/h9-11,16H,1-8H2,(H3,15,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 24: 5489-92 (2015) Article DOI: 10.1016/j.bmcl.2014.10.013 BindingDB Entry DOI: 10.7270/Q25M67B1
					More data for this Ligand-Target Pair