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SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)c3CCCc3[nH]2)c1O

InChI Key: InChIKey=RNZDPRPLOFMQLN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036748   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50036748
PNG
(CHEMBL3354825)
Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)c3CCCc3[nH]2)c1O
Show InChI InChI=1S/C16H18ClN3O4S/c1-8(2)25(23,24)14-10(17)6-7-12(13(14)21)19-16-18-11-5-3-4-9(11)15(22)20-16/h6-8,21H,3-5H2,1-2H3,(H2,18,19,20,22)
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Article
PubMed
n/an/a 2.51E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay

Bioorg Med Chem Lett 24: 5493-6 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.003
BindingDB Entry DOI: 10.7270/Q21V5GKV
More data for this
Ligand-Target Pair