BDBM50036750 2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol; with sodium ion::CHEMBL48667::Sodium salt of 2-Ethoxy-4-ethyl-5-[6-methyl-6-(2H-tetrazol-5-yl)-heptyloxy]-phenol::sodium 2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol
SMILES: CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
InChI Key: InChIKey=QDWLZEFMYHPCCB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound against human neutrophil Receptor. | Bioorg Med Chem Lett 5: 1995-2000 (1995) Article DOI: 10.1016/0960-894X(95)00340-Y BindingDB Entry DOI: 10.7270/Q2JW8DVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound against Guinea pig membrane LTB4 Receptor. | Bioorg Med Chem Lett 5: 1995-2000 (1995) Article DOI: 10.1016/0960-894X(95)00340-Y BindingDB Entry DOI: 10.7270/Q2JW8DVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay | Bioorg Med Chem Lett 2: 1669-1674 (1992) Article DOI: 10.1016/S0960-894X(00)80453-9 BindingDB Entry DOI: 10.7270/Q2PN95KG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]LTB4 receptor binding in guinea pig lung membrane | J Med Chem 36: 3978-81 (1993) Article DOI: 10.1021/jm00076a029 BindingDB Entry DOI: 10.7270/Q20V8G1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay | Bioorg Med Chem Lett 2: 1675-1680 (1992) Article DOI: 10.1016/S0960-894X(00)80454-0 BindingDB Entry DOI: 10.7270/Q2JW8DT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of LTB4-induced human neutrophil CD11b/CD18 integrin up-regulation | J Med Chem 36: 3978-81 (1993) Article DOI: 10.1021/jm00076a029 BindingDB Entry DOI: 10.7270/Q20V8G1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay | Bioorg Med Chem Lett 2: 1675-1680 (1992) Article DOI: 10.1016/S0960-894X(00)80454-0 BindingDB Entry DOI: 10.7270/Q2JW8DT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophils | Bioorg Med Chem Lett 2: 1675-1680 (1992) Article DOI: 10.1016/S0960-894X(00)80454-0 BindingDB Entry DOI: 10.7270/Q2JW8DT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity of the compound against human neutrophil Receptor. | Bioorg Med Chem Lett 5: 1995-2000 (1995) Article DOI: 10.1016/0960-894X(95)00340-Y BindingDB Entry DOI: 10.7270/Q2JW8DVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]LTB4 receptor binding in human neutrophils | J Med Chem 36: 3978-81 (1993) Article DOI: 10.1021/jm00076a029 BindingDB Entry DOI: 10.7270/Q20V8G1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50036750 (2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay | Bioorg Med Chem Lett 2: 1669-1674 (1992) Article DOI: 10.1016/S0960-894X(00)80453-9 BindingDB Entry DOI: 10.7270/Q2PN95KG | |||||||||||
More data for this Ligand-Target Pair |