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SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)-c2ccccc2Cl)c1O

InChI Key: InChIKey=OFWNHGRETWZKDQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036753   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50036753
PNG
(CHEMBL3354828)
Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)-c2ccccc2Cl)c1O
Show InChI InChI=1S/C19H17Cl2N3O4S/c1-10(2)29(27,28)18-13(21)7-8-14(17(18)26)22-19-23-15(9-16(25)24-19)11-5-3-4-6-12(11)20/h3-10,26H,1-2H3,(H2,22,23,24,25)
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n/an/a 631n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay

Bioorg Med Chem Lett 24: 5493-6 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.003
BindingDB Entry DOI: 10.7270/Q21V5GKV
More data for this
Ligand-Target Pair