BindingDB logo
myBDB logout

null

SMILES: CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)-c2cccn2C)c1O

InChI Key: InChIKey=BXTAEAOBDRNKGO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50036788
PNG
(CHEMBL3354830)
Show SMILES CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc([nH]2)-c2cccn2C)c1O
Show InChI InChI=1S/C18H19ClN4O4S/c1-10(2)28(26,27)17-11(19)6-7-12(16(17)25)20-18-21-13(9-15(24)22-18)14-5-4-8-23(14)3/h4-10,25H,1-3H3,(H2,20,21,22,24)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.51E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay

Bioorg Med Chem Lett 24: 5493-6 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.003
BindingDB Entry DOI: 10.7270/Q21V5GKV
More data for this
Ligand-Target Pair