BDBM50036796 CHEMBL3355234

SMILES: CC(C)Cc1cc(=O)nc(Nc2ccc(Cl)c(c2O)S(=O)(=O)C(C)C)[nH]1

InChI Key: InChIKey=JWAAZJGPZWZEJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50036796 (CHEMBL3355234) Show SMILES CC(C)Cc1cc(=O)nc(Nc2ccc(Cl)c(c2O)S(=O)(=O)C(C)C)[nH]1 Show InChI InChI=1S/C17H22ClN3O4S/c1-9(2)7-11-8-14(22)21-17(19-11)20-13-6-5-12(18)16(15(13)23)26(24,25)10(3)4/h5-6,8-10,23H,7H2,1-4H3,(H2,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 (unknown origin) by beta-arrestin assay				Bioorg Med Chem Lett 24: 5493-6 (2015) Article DOI: 10.1016/j.bmcl.2014.10.003 BindingDB Entry DOI: 10.7270/Q21V5GKV
					More data for this Ligand-Target Pair