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SMILES: Cc1nn(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12

InChI Key: InChIKey=MVSWAPHZZRDVCH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50036923 (2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES Cc1nn(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12 Show InChI InChI=1S/C24H27N5OS/c1-18-19-8-2-3-9-20(19)24(30)29(25-18)13-7-6-12-27-14-16-28(17-15-27)23-21-10-4-5-11-22(21)31-26-23/h2-5,8-11H,6-7,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralin				J Med Chem 37: 2552-63 (1994) BindingDB Entry DOI: 10.7270/Q2G15ZWF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50036923 (2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES Cc1nn(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12 Show InChI InChI=1S/C24H27N5OS/c1-18-19-8-2-3-9-20(19)24(30)29(25-18)13-7-6-12-27-14-16-28(17-15-27)23-21-10-4-5-11-22(21)31-26-23/h2-5,8-11H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Company Curated by ChEMBL					Assay Description In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley rats				J Med Chem 37: 2552-63 (1994) BindingDB Entry DOI: 10.7270/Q2G15ZWF
					More data for this Ligand-Target Pair