BDBM50037526 CHEMBL3357194

SMILES: COc1cc(O)c(C(=O)OCC2CCCCC2)c(\C=C\CN2C(=O)C=CC2=O)c1

InChI Key: InChIKey=FFRTZPOZWGTAJA-VMPITWQZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50037526 (CHEMBL3357194) Show SMILES COc1cc(O)c(C(=O)OCC2CCCCC2)c(\C=C\CN2C(=O)C=CC2=O)c1 |c:25| Show InChI InChI=1S/C22H25NO6/c1-28-17-12-16(8-5-11-23-19(25)9-10-20(23)26)21(18(24)13-17)22(27)29-14-15-6-3-2-4-7-15/h5,8-10,12-13,15,24H,2-4,6-7,11,14H2,1H3/b8-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assay				Bioorg Med Chem 22: 6625-37 (2015) Article DOI: 10.1016/j.bmc.2014.10.006 BindingDB Entry DOI: 10.7270/Q2C53NG1
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50037526 (CHEMBL3357194) Show SMILES COc1cc(O)c(C(=O)OCC2CCCCC2)c(\C=C\CN2C(=O)C=CC2=O)c1 |c:25| Show InChI InChI=1S/C22H25NO6/c1-28-17-12-16(8-5-11-23-19(25)9-10-20(23)26)21(18(24)13-17)22(27)29-14-15-6-3-2-4-7-15/h5,8-10,12-13,15,24H,2-4,6-7,11,14H2,1H3/b8-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant FLT3 D835Y mutant (unknown origin) by TR-FRET assay				Bioorg Med Chem 22: 6625-37 (2015) Article DOI: 10.1016/j.bmc.2014.10.006 BindingDB Entry DOI: 10.7270/Q2C53NG1
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50037526 (CHEMBL3357194) Show SMILES COc1cc(O)c(C(=O)OCC2CCCCC2)c(\C=C\CN2C(=O)C=CC2=O)c1 |c:25| Show InChI InChI=1S/C22H25NO6/c1-28-17-12-16(8-5-11-23-19(25)9-10-20(23)26)21(18(24)13-17)22(27)29-14-15-6-3-2-4-7-15/h5,8-10,12-13,15,24H,2-4,6-7,11,14H2,1H3/b8-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant FLT3 ITD mutant (unknown origin) by RBC kinase assay				Bioorg Med Chem 22: 6625-37 (2015) Article DOI: 10.1016/j.bmc.2014.10.006 BindingDB Entry DOI: 10.7270/Q2C53NG1
					More data for this Ligand-Target Pair