BDBM50037582 7-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethyl]-3,4-dihydro-2H-naphthalen-1-one::CHEMBL117782

SMILES: O=C(Cc1ccc2CCCC(=O)c2c1)N1CCCC[C@H]1CN1CCCC1

InChI Key: InChIKey=STMCSVQZUYGQII-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Mus musculus (Mouse))	BDBM50037582 (7-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) Show SMILES O=C(Cc1ccc2CCCC(=O)c2c1)N1CCCC[C@H]1CN1CCCC1 Show InChI InChI=1S/C22H30N2O2/c25-21-8-5-6-18-10-9-17(14-20(18)21)15-22(26)24-13-2-1-7-19(24)16-23-11-3-4-12-23/h9-10,14,19H,1-8,11-13,15-16H2/t19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL					Assay Description Evaluated for the binding affinity at kappa receptor				J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6
					More data for this Ligand-Target Pair