BDBM50037592 6-(2-{(S)-2-[(Methyl-prop-2-ynyl-amino)-methyl]-piperidin-1-yl}-2-oxo-ethyl)-3,4-dihydro-2H-naphthalen-1-one::CHEMBL326540

SMILES: CN(CC#C)C[C@@H]1CCCCN1C(=O)Cc1ccc2C(=O)CCCc2c1

InChI Key: InChIKey=AOFFWXCMEOFKFK-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Mus musculus (Mouse))	BDBM50037592 (6-(2-{(S)-2-[(Methyl-prop-2-ynyl-amino)-methyl]-pi...) Show SMILES CN(CC#C)C[C@@H]1CCCCN1C(=O)Cc1ccc2C(=O)CCCc2c1 Show InChI InChI=1S/C22H28N2O2/c1-3-12-23(2)16-19-8-4-5-13-24(19)22(26)15-17-10-11-20-18(14-17)7-6-9-21(20)25/h1,10-11,14,19H,4-9,12-13,15-16H2,2H3/t19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL					Assay Description Evaluated for the binding affinity at kappa receptor				J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6
					More data for this Ligand-Target Pair