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SMILES: CCCCCCCCNC(=O)N(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)c1ccc(F)cc1F

InChI Key: InChIKey=PZJHEZDVOLCVRP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037615   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50037615
PNG
(1-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Show SMILES CCCCCCCCNC(=O)N(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)c1ccc(F)cc1F
Show InChI InChI=1S/C35H42F2N4OS/c1-2-3-4-5-6-14-23-38-35(42)41(31-22-21-29(36)26-30(31)37)24-15-9-16-25-43-34-39-32(27-17-10-7-11-18-27)33(40-34)28-19-12-8-13-20-28/h7-8,10-13,17-22,26H,2-6,9,14-16,23-25H2,1H3,(H,38,42)(H,39,40)
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PubMed
n/an/a 40n/an/an/an/an/an/a



DuPont Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes

J Med Chem 37: 3511-22 (1994)


BindingDB Entry DOI: 10.7270/Q2MK6BXK
More data for this
Ligand-Target Pair