BDBM50037892 CHEMBL3358262

SMILES: CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)NC(=O)c1cc(C)oc1C1CC1

InChI Key: InChIKey=PKJCNVBPDXZMDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIFC1 (Homo sapiens (Human))	BDBM50037892 (CHEMBL3358262) Show SMILES CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)NC(=O)c1cc(C)oc1C1CC1 Show InChI InChI=1S/C29H32F3N3O3/c1-18-15-24(26(38-18)21-11-12-21)27(36)34-25(28(37)33-13-14-35(2)3)16-19-7-9-20(10-8-19)22-5-4-6-23(17-22)29(30,31)32/h4-10,15,17,21,25H,11-14,16H2,1-3H3,(H,33,37)(H,34,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...				J Med Chem 57: 9958-70 (2014) Article DOI: 10.1021/jm501179r BindingDB Entry DOI: 10.7270/Q2QF8VG8
					More data for this Ligand-Target Pair