BDBM50037894 CHEMBL3358260

SMILES: CCOc1cccc(c1)C(=O)NC(Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(=O)NCCN(C)C

InChI Key: InChIKey=UBXTYMUIQFZANS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIFC1 (Homo sapiens (Human))	BDBM50037894 (CHEMBL3358260) Show SMILES CCOc1cccc(c1)C(=O)NC(Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(=O)NCCN(C)C Show InChI InChI=1S/C29H32F3N3O3/c1-4-38-25-10-6-8-23(19-25)27(36)34-26(28(37)33-15-16-35(2)3)17-20-11-13-21(14-12-20)22-7-5-9-24(18-22)29(30,31)32/h5-14,18-19,26H,4,15-17H2,1-3H3,(H,33,37)(H,34,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...				J Med Chem 57: 9958-70 (2014) Article DOI: 10.1021/jm501179r BindingDB Entry DOI: 10.7270/Q2QF8VG8
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