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BDBM50037900 CHEMBL3358254

SMILES: CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1nccn1C)NC(=O)c1ccccc1OCc1ccccc1

InChI Key: InChIKey=IWAIXWWOFXRIMW-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037900   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037900
PNG
(CHEMBL3358254)
Show SMILES CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1nccn1C)NC(=O)c1ccccc1OCc1ccccc1
Show InChI InChI=1/C31H35N5O3/c1-35(2)19-17-33-31(38)27(21-23-13-15-25(16-14-23)29-32-18-20-36(29)3)34-30(37)26-11-7-8-12-28(26)39-22-24-9-5-4-6-10-24/h4-16,18,20,27H,17,19,21-22H2,1-3H3,(H,33,38)(H,34,37)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair